Cystatin C is a biomarker for kidney function that researchers first described in patients with reduced kidney function and later expanded to include children with increased levels of hematuria. Cystatin C can serve as an indicator for cystinosis, which is a rare genetic disease, affecting about one out of 100,000 individuals. The Cysteine Protease inhibitor, cystatin C, or CysC is encoded by the CST3 gene found on chromosome. Cystatin C is a kidney biomarker used to assess glomerular filtration rate, adrenal functions, and cardiovascular diseases. Cystatin is a non-glycosylated protein. It is mainly found in the urine of individuals with renal failure or heart disease illnesses.
What is cystatin C test? A common question asked by patients who have been diagnosed with chronic kidney disease is what is cystatin c test and what does the test result mean? Cystatin c kidney function is primarily used to evaluate kidney functions. The results of the cystatin C test are used in conjunction with other blood tests and other information to diagnose, manage, or monitor patients with kidney diseases. The cystatin C test also helps to determine the severity of renal diseases and assesses patients for end-stage renal disease.
Geriatricians use Cystatin C to detect chronic kidney disease and kidney diseases that are more severe than previously diagnosed. Normally, the glomerular filtration rate (GFR) is about 125 mL/min for women and about 140 mL/min for men. The GFR correlates to the amount of plasma filtered through all the nephrons in one minute, i.e. it records all of the plasma dumped into urine per minute. At this rate, 100 mL of blood is constantly being slaked through the kidneys to remove excess water and blood cells, prolonging life span.
Hepatocyte Growth Factor (HGF) is a paracrine protein encoded by the HGF gene. HGF gene is present on chromosome 7. HGF is motility, cellular growth, and morphogenic factor. Even though HGF is a part of the plasminogen subfamily of S1 peptidase, it does not have any protease activity. HGF is a single inactive polypeptide, and serine proteases cleave it into a 69-kilodalton α-chain and 34-kilodalton β-chain. A disulfide bond formed between the αβ-chain creates an active heterodimeric protein.
Hepatocyte Growth Factor (HGF) is also known as scatter factor and is a paracrine protein. HGF is motility, cellular growth, and morphogenic factor. Bio hgf forte uses though HGF is a part of the plasminogen sub-family of S1 peptidase, it does not have any protease activity. HGF is a single inactive polypeptide, and serine proteases cleave it into α-chain and β-chain. A disulfide bond formed between the αβ-chain creates an active heterodimeric protein.
Hepatocyte Growth Factor (HGF), isolated from porcine small intestine, is a very potent hepatopoietic agent. It can induce differentiation of hepatocyte cell with high efficiency and has a wide range of hepatopoiesis inducing effects.
Hepatocyte Growth Factor (HGF) is a paracrine protein encoded by the HGF gene. HGF is also known as scatter factor and plays an important role in organ development in embryos, wound healing, and organ regeneration in adults. It works by activating different cell-surface receptors on specific cells such as endothelial, epithelial or mesenchymal cells.
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